The Ministry of Health, Labour and Welfare has introduced mandatory requirement for safety assessment of foods and food additives produced by recombinant DNA techniques. It also requested the Food Safety Investigation Council to discuss the necessity for labelling of foods and food additives produced by recombinant DNA techniques in view of public health. The following food additives are been recently reviewed and assessed by the Ministry of Health, Labour and Welfare: * alpha-amylase TS-25, BSG-amylase, and TMG amylase, by Novo Nordisk A/S (Denmark) * Rennet Maxiren by Gist-Brocades N.V. (Netherlands) * Pullulanase Optimax by Genecor International, Inc. (USA) * Lipase SP388 by Novo Nordisk A/S (Denmark) * Riboflavin Vitamin B2 by F.Hoffmann-La Roche Ltd. (Switzerland)
